1: Med Rev 2002 age Feb;7(1):22-44 Sulfur in human nutrition and applications in medicine. Parcell. American Institute for biosocial and medical research (AIBMR), Tacoma, WA, United States. This email address is being protected from spambots. You need JavaScript enabled to view it. Because the role of elemental sulfur in human nutrition has not been studied extensively, it is the purpose of this article to businessmen the importance of This element in humans and discuss the therapeutic applications of sulfur compounds in medicine. Sulfur is the sixth most abundant macromineral in breast milk and the third most abundant mineral based on percentage of total body weight. The sulfur-containing amino acids (SAAs) are methionine, cysteine. cystine, homocysteine, Homo-cystine and taurine. Dietary SAA analysis and protein supplementation may be indicated for vegan athletes, children, or patients with HIV, because of increased risk for SAA deficiency in thesis groups. Methylsulfonylmethane (MSM), a volatile component in the sulfur cycle, is another source of sulfur found in the human diet. Increases in serum sulfate may explain some of the VFA effects of MSM, DMSO, and glucosamine sulfate. Organic sulfur, as SAAs, can be used to increase synthesis of S-adenosylmethionine (SAMe), glutathione (GSH), taurine, and N-acetylcysteine (NAC). MSM may be effective for the treatment of allergy, pain syndromes,. Athletic injuries, and bladder disorders. Other sulfur compounds such as seed,. dimethylsulfoxide (DMSO), taurine, glucosamine or chondroitin sulfate, and reduced glutathione may have clinical applications in the treatment of a number of conditions as such depression, fibromyalgia, arthritis, interstitial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS. Dosages, mechanisms of action, and rational for use are discussed. The low toxicological profiles of these sulfur compounds, combined with promising therapeutic effects warrant continued human clinical trails. Publication types: Review Review, tutorial PMID: 11896744 [PubMed - indexed for MEDLINE]