Arnold LE, Christopher J, Huestis RD, Smeltzer DJ.

Preliminary to a stimulant comparison study, 31 children with minimal brain dysfunction randomly received either placebo or a megavitamin combination.

During a two-week trial, only two children responded so well that stiumlants were not considered necessary; both were in the placebo group. Change scores from pretest to posttest on four blind ratings by teachers and parents did not show a significant difference between the placebo and vitamin groups.

Publication Types: Clinical Trial Randomized Controlled Trial

JAMA 1978 Dec 8;240(24):2642-3
PMID: 712981 [PubMed - indexed for MEDLINE]